How To Use Weight Loss Medications?

How to use Weight Loss Medications:

It is important to note that these medications should only be prescribed by a doctor and will work with a controlled diet and exercise program.

Please see below for a guide on how to use the different types of Weight Loss / Anti-Obesity Medications.


Oral Tablets:

Duromine (Phentermine)

  • Dosage: 15–30 mg weekly
  • Expected weight loss: 5–10% total weight loss over 12 weeks (Kang et al. 2010)
  • Not PBS listed


Contrave (Naltrexone/Bupropion)

  • Dosage: 8 mg/90 mg daily, increasing up to 4 tablets per day
  • Expected weight loss: 5.4% total weight loss over 56 weeks (Greenway et al. 2010)
  • Not PBS listed


Topamax (Topiramate)

  • Dosage: 25–200 mg daily
  • Expected weight loss: 5% total weight loss over 24 weeks (Bray et al. 2003)
  • TGA approved for migraines and epilepsy, not PBS listed for weight loss


Injectable Medications:

Mounjaro (Tirzepatide)

  • Dosage: 2.5–15 mg weekly
  • Expected weight loss: 15–20.9% total weight loss over 72 weeks (Surmount Trials)
  • TGA approved for type 2 diabetes, not PBS listed for weight loss


Wegovy (Semaglutide)

  • Dosage: 0.25–2.4 mg weekly
  • Expected weight loss: 14.9–18.5% total weight loss over 68–208 weeks (Step 1–4, 5, 8, and Select Trials)
  • TGA approved for weight loss, not PBS listed


Ozempic (Semaglutide)

  • Dosage: 0.25–1 mg weekly
  • Expected weight loss: 6.5% total weight loss over 40 weeks (Sustain 7 Trials)
  • PBS listed for type 2 diabetes, not PBS listed for weight loss


Saxenda (Liraglutide)

  • Dosage:  0.6–3 mg daily
  • Expected weight loss: 6.4–8% total weight loss over 56–68 weeks (Step 8, Scale, and Leader Trials)
  • TGA approved for weight loss, not PBS listed for weight loss


Trulicity (Dulaglutide)

  • Dosage: 1.5 mg weekly
  • Expected weight loss: 3% total weight loss over 40 weeks (Sustain 7 Trials)
  • TGA approved for weight loss, PBS listed for type 2 diabetes