How To Use Weight Loss Medications?
How to use Weight Loss Medications:
It is important to note that these medications should only be prescribed by a doctor and will work with a controlled diet and exercise program.
Please see below for a guide on how to use the different types of Weight Loss / Anti-Obesity Medications.
Oral Tablets:
Duromine (Phentermine)
- Dosage: 15–30 mg weekly
- Expected weight loss: 5–10% total weight loss over 12 weeks (Kang et al. 2010)
- Not PBS listed
Contrave (Naltrexone/Bupropion)
- Dosage: 8 mg/90 mg daily, increasing up to 4 tablets per day
- Expected weight loss: 5.4% total weight loss over 56 weeks (Greenway et al. 2010)
- Not PBS listed
Topamax (Topiramate)
- Dosage: 25–200 mg daily
- Expected weight loss: 5% total weight loss over 24 weeks (Bray et al. 2003)
- TGA approved for migraines and epilepsy, not PBS listed for weight loss
Injectable Medications:
Mounjaro (Tirzepatide)
- Dosage: 2.5–15 mg weekly
- Expected weight loss: 15–20.9% total weight loss over 72 weeks (Surmount Trials)
- TGA approved for type 2 diabetes, not PBS listed for weight loss
Wegovy (Semaglutide)
- Dosage: 0.25–2.4 mg weekly
- Expected weight loss: 14.9–18.5% total weight loss over 68–208 weeks (Step 1–4, 5, 8, and Select Trials)
- TGA approved for weight loss, not PBS listed
Ozempic (Semaglutide)
- Dosage: 0.25–1 mg weekly
- Expected weight loss: 6.5% total weight loss over 40 weeks (Sustain 7 Trials)
- PBS listed for type 2 diabetes, not PBS listed for weight loss
Saxenda (Liraglutide)
- Dosage: 0.6–3 mg daily
- Expected weight loss: 6.4–8% total weight loss over 56–68 weeks (Step 8, Scale, and Leader Trials)
- TGA approved for weight loss, not PBS listed for weight loss
Trulicity (Dulaglutide)
- Dosage: 1.5 mg weekly
- Expected weight loss: 3% total weight loss over 40 weeks (Sustain 7 Trials)
- TGA approved for weight loss, PBS listed for type 2 diabetes







